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Bio21: Teaching Biology with Bioinformatics


October 17-18th, 2003 Chapel Hill, North Carolina

Workshop Descriptions

Friday

Title: Funding Opportunities at the National Science Foundation and Tips for Writing Successful Proposals

Presenter: V. Celeste Carter, Ph.D., Biotechnology and Bioinformatics Program Director Division of Biological and Health Sciences, Foothill College, CA

Description: Dr. Carter will talk about her experience as a program officer at the National Science Foundation and describe the NSF's programs for funding educational activities and curriculum development. The workshop will include information about applying for funding and the important points to consider.

Presentation:

Funding Opportunities at the National Science Foundation and Tips for Writing Successful Proposals (.ppt, 1.7 Mb)

Title: OnLine Bio-Databases & Bioinformatics Tools for the Educator

Presenter: Christopher Smith, Ph.D., Program Manager, Integrative BioSciences / Integrative Computational Sciences, San Diego Supercomputer Center, University of California San Diego, CA

Description: An overview of the plethora of biology-related databases and bioinformatics tools will be presented, as well as web portals and guides that provide educator-friendly interfaces to the plethora of resources. The focus of this workshop will be a presentation on and hands-on activity detailing how these tools have been integrated into laboratory/classroom activities.

CMSMolecular Biology Resource: http://restools.sdsc.edu
CMSMBR Discovery Tools: http://restools.sdsc.edu/discovery_tools/discovery_tools.html
Using Internet Resources in Molecular Biology:
http://www.sdsc.edu/pb/edu/pharm207/7/7.html

Presentation:

Online Databases and Bioinformatics Tools for the Educator (.ppt, 2.1 Mb)

Title: Analysis of Microarray Data in the Classroom

Presenter: Laurie Heyer, Ph.D., Department of Mathematics Davidson College, Davidson, NC

Description: Dr. Heyer will lead participants through the process of analyzing microarray data using MAGIC Tool, a program developed in her laboratory. MAGIC Tool is described in more detail at http://www.bio.davidson.edu/magic

Title: Bioinformatics resources at Geospiza and the Dolan DNA Learning Center at Cold Spring Harbor Laboratory

Presenters: Linnea Fletcher, Ph.D., Bio-Link Regional Director, and Biotechnology Program Director, Austin Community College, Austin, TX

Description: Computers have become a standard piece of equipment in modern biology labs. We use them to control laboratory equipment; to gather, store and analyze data; and to share our results with others over the Internet. Now, with a wealth of data from genome and proteome projects, students can do hypothesis-driven and discovery-based research, as well. Some of the most widely used bioinformatics tools have been those that allow biologists to search literature, compare biological sequences, and visualize the organization of genes and introns and models of three-dimensional structures.

Dr. Linnea Fletcher has investigated and used a wide variety of materials that are available for instructors who wish to use bioinformatics in their classes. These include the Green Arrow® Tutorials (Geospiza, Inc.), DNA interactive (Cold Spring Harbor Laboratories), the Biology Student Workbench, and others. In this workshop, Linnea Fletcher will provide an overview of existing materials and illustrate how she uses bioinformatics in several courses in her biotechnology program.

Presentation:

Green Arrow Tutorials    http://www.geospiza.com/outreach

DNA interactive    http://www.dnai.org

Biology Student Workbench    http://peptide.ncsa.uiuc.edu

Saturday

Title: NCBI WWW Genome Resources in the Biology Curriculum

Presenter: Peter Cooper, Ph.D., National Center for Biotechnology Information

Description: Molecular databases and analysis tools available on the World Wide Web are now invaluable resources for biological research. Familiarity with these resources is expected for all working in the biological sciences. Undergraduate students in biology therefore should receive as much experience as possible in the use of these online resources. Moreover, the availability of, well-annotated, complete mammalian genomes provides a rich area for exploration and valuable learning experiences that can be used to enhance and reinforce the key concepts in a wide variety of undergraduate life science settings.

This tutorial will provide participants with instructor-led hands-on practice using the molecular biology databases and tools available at the National Center for Biotechnology Information. Participants will gain experience using worked examples designed to be easily incorporated into undergraduate courses. The focus will be on complete genomes and emphasize the integration of various types of data, including literature, sequence and structure, and analysis tools, including the NCBI BLAST services.

Presentation:

NCBI Resources in Bioinformatics Education (.ppt, 8.9 Mb)

NCBI Resources in Bioinformatics Education (.pdf, 2 Mb)

NCBI Handout and Problem Set (.pdf, 3 Mb)

Title: BEDROCK

Presenter: Sam Donovan, Ph.D., BEDROCK, BioQUEST Curriculum Consortium, University of Pittsburgh, Department of Instruction and Learning, Pittsburgh, PA

Description: The National Science Foundation funded BEDROCK initiative (Bioinformatics Education Dissemination: Reaching Out, Connecting and Knitting-together) is a new BioQUEST project with the goal of enhancing, expanding, and empowering a national community of bioinformatics educators.

Presentation:

http://bioquest.org/bedrock

Title: Exploring DNA Land with Regular Expressions

Presenter: Mark LeBlanc, Ph.D., Computer Science, and Betsey Dyer, Ph.D., Department of Biology; Wheaton College, Norton, MA

Description: We have developed a set of lab exercises to teach students to write regular expressions (RegEx) useful in searching files of DNA sequences. Our central theme is "word play". Students visualize the results of their searches by applying regular expressions to both English word lists and DNA motif lists. We have found that the enjoyment of seeing patterns in words (and in motifs) is an excellent motivator for learning RegEx syntax and using it for creative exploration. Participants in this workshop will quickly learn some basic RegEx rules and will use them to seek interesting words and motifs.

Presentation:

Regular Expression Lab (.pdf, 412 kb)

Title: Phylogenetics in the Classroom

Presenter: Stuart Brown, Ph.D., Research Computing Resource, NYU School of Medicine, NY, NY

Description: This workshop will contain both a lecture and practical exercises so that attendees will become familiar with both the theory and practical aspects of building phylogenetic trees from molecular sequence data. First we will look at the history of taxonomic classification and the theoretical basis of grouping organisms by the number of shared characters (cladistics). Then we will examine the relationship between sequence alignment, clustering, and the various phylogentic algorithms (simple similarity, neighbor joining, parsimony, and maximum likelihood). Finally, we will look at a range of phylogenetics computer software that is available for free download and on the Web.

Presentation:

Phylogeny workshop powerpoint slides (.ppt, 564 kb)

Phylogeny workshop web page

 
 
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