BIOINFORMATICS REFERENCE ARTICLES

BLAST

COGS

Evolution

Structure

BLAST

Checking the Alignment
Jane Salodof MacNeil
The Scientist 2003 17:September 22, 2003

Having a BLAST with bioinformatics (and avoiding BLASTphemy)
Alexander Pertsemlidis and John W Fondon III, Eugene McDermott
Genome Biology 2001 2:reviews2002.1-2002.10

COGs

The COG database: an updated version includes eukaryotes
Tatusov RL, Fedorova ND, Jackson JD, Jacobs AR, Kiryutin B, Koonin EV, Krylov DM, Mazumder R, Mekhedov SL, Nikolskaya AN, Rao BS, Smirnov S, Sverdlov AV, Vasudevan S, Wolf YI, Yin JJ, Natale DA
BMC Bioinformatics. 2003 Sep 11;4(1):41.

Evolution
Phylogeny collection
A fantastic collection of articles from the Evolutionary Biology Group at the University of Oxford

Comparing methods for inferring phylogenies

Conservation biology

Epidemiology and viral evolution

  • Hepatitis C virus
    To get a listing of interesting articles, copy the query below, then paste it in the text box at PubMed
    "journal of clinical microbiology"[Journal] AND HCV[Title/Abstract] AND phylogenetic[Title/Abstract]

  • Outbreak of Nosocomial Hepatitis C Virus Infection Resolved by Genetic Analysis of HCV RNA.
    Bruguera,M., Saiz,J.C., Franco,S., Gimenez-Barcons,M., Sanchez-Tapias,J.M., Fabregas,S., Vega,R., Camps,N., Dominguez,A., Salleras,L.
    J. Clin. Microbiol. 40 (11), 4363-4366 (11 2002)

  • Identification of I50L as the Signature Atazanavir (ATV)Resistance Mutation in Treatment-Naive HIV-1Infected Patients Receiving ATV-Containing Regimens
    Colonno,R., Rose,R., McLaren,C., Thiry,A., Parkin,N., Friborg,J.
    J. Infect. Dis. 189 (10), 1802-1810 (2004)

  • Selection of high-level resistance to human immunodeficiency virus type 1 protease inhibitors
    Watkins,T., Resch,W., Irlbeck,D., Swanstrom,R.
    Antimicrob. Agents Chemother. 47 (2), 759-769 (2 2003)

Human evolution

Molecular Clock

SNPs and selection tests

Technical considerations in phylogenetic methods

Structure
  • Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes.
    Matthews DA, Dragovich PS, Webber SE, Fuhrman SA, Patick AK, Zalman LS, Hendrickson TF, Love RA, Prins TJ, Marakovits JT, Zhou R, Tikhe J, Ford CE, Meador JW, Ferre RA, Brown EL, Binford SL, Brothers MA, DeLisle DM, Worland ST.
    Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11000-7

  • The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor.
    Yang H, Yang M, Ding Y, Liu Y, Lou Z, Zhou Z, Sun L, Mo L, Ye S, Pang H, Gao GF, Anand K, Bartlam M, Hilgenfeld R, Rao Z.
    Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13190-5.

  • Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs.
    Anand K, Ziebuhr J, Wadhwani P, Mesters JR, Hilgenfeld R.
    Science. 2003 Jun 13;300(5626):1763-7.

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