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Allelic
variants of Superoxide Dismutase |
Learn to:
Do
a BLAST search of the human genome
Use
LocusLink
Locate
information about a genetic disease and find allelic variants
of a gene
Locate
information in a database of scientific literature
Find
where a mutation is located within the three dimensional
structure of a protein using Cn3D
Use
NCBI's Genes and Disease section as a classroom resource
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BLAST
for beginners |
A painless introduction for those
who have never used BLAST. A set of test sequences is supplied
at the end.
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Cancer Biology |
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Learn how to:
Use Entrez to efficiently locate scientific articles
in PubMed
Learn about MeSH (Medical Subject Headings)
Use Boolean operators (AND, OR, NOT), the wildcard operator
(*), and how to combine search terms
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Introduction
to Protein Structure |
Learn:
How to use Cn3D - an application for viewing and comparing
protein structures
How to find structures in the molecular modeling database (MMDB)
About the different levels of protein structure
About the relationship between the structure and function
of a protein
About the relationship between the amino acid sequence
and physical properties of a protein (charge, hydrophobicity,
element, etc.)
About protein secondary and quarternary structure
How a gene sequence corresponds to a
protein sequence
Compare protein structures to DNA structures
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Mitochondria
and Chloroplasts |
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Learn how to:
Use bioinformatics tools to study mitochondria and chloroplasts
Study maternal inheritance
Compare human mitochondria with mitochondria from other
animals
Learn about human evolution
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SNP
or Sequencing Error? |
Use
information from phred to evaluate sequence quality
Use
information about phrap assemblies to evaluate assemblies
and to find potential polymorphisms
Use
the CGAP SNP index as a tool for evaluating potential SNPs
Use
dbSNP and BLAST to evaluate potential SNPs
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Two
Windows |
Web-based bioinformatics tools are easier to use when
you've mastered some simple tricks with your web browser.
This tutorial shows how to open 2 web browser windows at
the same time and move back and forth.
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Graphing Scientific Data
with Microsoft Excel |
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Part I. Prepare a straight
line plot using Microsoft Excel and get the correct values
on the both the X and Y axis.
Part II. Prepare and
edit a semi-log plot with the log scale on the Y axis.
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Funding
for this project was provided by the National Science Foundation's
Course, Curriculum, and Laboratory Improvement Program under
grants DUE-0088153 and DUE-0127599, also from Bio-Link,
an NSF Advanced Technology Education Center.
Any
opinions, finding, and conclusions or recommendations expressed
in this material are those of the author and do not necessarily
reflect the views of the National Science Foundation. |
